ACTH-induced excessive grooming in the rat: the influence of environmental and motivational factors.
نویسندگان
چکیده
Intraventricularly administered ACTH,.,, in rats initiated excessive grooming followed by stretching and yawning syndrome. The present study provides evidence that novelty is not an essential prerequisite for its expression and that a variety of environmental variables is not able to influence the peptide-induced behavior. Only very strong motivational variables as severe hunger/thirst and anxiety are able to modulate the ACTH-initiated excessive grooming: This response is significantly depressed in water-deprived rats bar pressing for water in a Skinner box, as well as in rats receiving unavoidable electric foot shock. The results are indicative of the strength of the ACTH-initiated motivation to groom, and it is suggested that excessive grooming is a secondary response serving to dearouse the organism after activation by ACTH.
منابع مشابه
بررسی عوامل مؤثر بر ماندگاری سازمانی نیروی انسانی
One of the most important tasks of the Human Resource Management (HRM) is employee retention. Hence, turnover rate is used to evaluate the HRM’s performance, and it is considered to be ok where the turnover rate is normal. However there exists another side for the coin which has got a lot to do with the reasons why the employees remain in the organization. By no doubt, the employee retention ba...
متن کاملUse of Colchicine in Cortical Area 1 of the Hippocampus Impairs Transmission of Non-Motivational Information by the Pyramidal Cells
Colchicine, a potent neurotoxin derived from plants, has been recently introduced as a degenerative toxin of small pyramidal cells in the cortical area 1 of the hippocampus (CA1). In this study, the effect of the alkaloid in CA1 on the behaviors in the conditioning task was measured. Injections of colchicine (1,5 μg/rat, intra-CA1) was performed in the male Wistar rats, while the animals were s...
متن کاملHippocampal lesions, haloperidol, and excessive grooming
Rats with bilateral hippocampal damage, neocortical lesions, or sham operations were tested for excessive grooming after intracerebroventricular (icv) injection of ACTH'-14 or saline. The animals were tested for 3 days after pretreatment with low doses of haloperidol and on the first and last test days after saline pretreatment. The animals with hippocampal lesions evidenced less grooming than ...
متن کاملارائه الگویی برای سنجش عوامل انگیزشی درونی و بیرونی مؤثر در تمایل کارکنان به تسهیم دانش
This study aimed to identify the motivational factors affecting the willingness of employees to share knowledge and examine intrinsic and extrinsic motivational factors and influences on attitudes toward knowledge sharing and explicit and implicit knowledge sharing intention. Planned behavior pattern is used as a theoretical framework. This research was conducted in two phases. First, factors w...
متن کاملEffects of Quercetin and ACTH on Morphine-Induced Tolerance and Dependence in Mice
The goal of this study was to evaluate the effects of quercetin and ACTH injection on prevention of development of morphine tolerance and dependence in mice. In this study different groups of mice received morphine (40 mg/kg, i.p.) plus quercetin (5, 10, 25 mg/kg, ip), ACTH (1, 2.5, 5 IU/mice, i.p.), or combination of quercetin (5 mg/kg) and ACTH (1 IU/mice) once a day for four days. Toler...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Hormones and behavior
دوره 12 1 شماره
صفحات -
تاریخ انتشار 1979